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[狂犬病病毒若干毒株多肽的聚丙烯酰胺凝胶分子研究]

[Molecular study in polyacrylamide gel of polypeptides of several strains of rabies virus].

作者信息

Arita M, Atanasiu P

出版信息

C R Seances Acad Sci D. 1980 Feb 18;290(7):515-8.

PMID:6771049
Abstract

Comparative study of structural polypeptides of five rabies virus strains (serotype 1) and one serotype IV, demonstrates difference in molecular weight of the envelope polypeptides M1 and G of all strains. There is little difference between the structural polypeptides N, M2 and probably L. Some purified strains have been treated by trypsine to localize the position of polypeptides. There was no difference between the four major polypeptides of complete and defective virus. Pasteur strain cultivated on different cells shows very little difference in molecular weight of the four major polypeptides.

摘要

对五株狂犬病病毒1型毒株和一株IV型毒株的结构多肽进行的比较研究表明,所有毒株包膜多肽M1和G的分子量存在差异。结构多肽N、M2以及可能的L之间差异不大。一些纯化毒株已用胰蛋白酶处理以确定多肽的位置。完整病毒和缺陷病毒的四种主要多肽之间没有差异。在不同细胞上培养的巴斯德毒株的四种主要多肽分子量差异很小。

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