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巴伐利亚州献血者血清学甲型和乙型肝炎标志物的流行情况(作者译)

[Prevalence of serological hepatitis A and B markers in Bavarian blood donors (author's transl)].

作者信息

Frösner G G, Weiss M, Scheid R, Deinhardt F, Gathof G A, Bäcker U, Gossrau E, Bär A

出版信息

MMW Munch Med Wochenschr. 1980 Feb 15;122(7):231-3.

PMID:6771630
Abstract

Sera from 1966 Bavarian blood donors were investigated by radioimmunoassay for serological markers of past hepatitis A and B infections. The prevalence of hepatitis A antibody increased with age and was higher in the urban than in rural populations. More than 80% of persons above 40 years of age had antibody whereas only few young adults showed previous exposure to hepatitis a virus. 20 of 1093 random persons (1.8%) were HBsAg positive at first blood donation. In all age groups anti-HBc was the best marker for previous hepatitis B exposure. There was no correlation between the frequency of hepatitis A and B markers.

摘要

采用放射免疫分析法对1966年巴伐利亚献血者的血清进行检测,以寻找既往甲型和乙型肝炎感染的血清学标志物。甲型肝炎抗体的流行率随年龄增长而升高,城市人群高于农村人群。40岁以上人群中超过80%有抗体,而只有少数年轻人显示曾接触过甲型肝炎病毒。1093名随机抽取的献血者中,有20人(1.8%)首次献血时HBsAg呈阳性。在所有年龄组中,抗-HBc是既往接触乙型肝炎的最佳标志物。甲型和乙型肝炎标志物的出现频率之间没有相关性。

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