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含短杆菌肽、丁卡因、苯海拉明和8-羟基喹啉的烧伤及创伤用凝胶的抗菌活性(作者译)

[The antibacterial activity of a gel for burns and wounds containing tyrothricin, fomocaine, diphenhydramine and 8-hydroxyquinoline (author's transl)].

作者信息

Knothe H, Beckmann I, Kiesel K, Oelschläger H

出版信息

Arzneimittelforschung. 1980;30(4):667-70.

PMID:6772197
Abstract

The antibacterial activity of a new jelly for burns and wounds with the components tyrothricin, 8-hydroxyquinoline, fomocaine and diphenhydramine (Herit) is described. The biological availability of tyrothricin and 8-hydroxyquinoline from the gel is in accordance with minimum inhibitor concentrations (MIC). Against strains of Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans the jelly was most effective.

摘要

描述了一种含短杆菌肽、8-羟基喹啉、甲磺酸苯酰吗啉和苯海拉明(Herit)的新型烧伤和伤口用凝胶的抗菌活性。凝胶中短杆菌肽和8-羟基喹啉的生物利用度符合最低抑菌浓度(MIC)。该凝胶对金黄色葡萄球菌、铜绿假单胞菌和白色念珠菌菌株最为有效。

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