气相色谱法测定人乳中的有机氯农药和多氯联苯。

Gas-liquid chromatographic determination of organochlorine pesticides and polychlorinated biphenyls in human milk.

作者信息

Tessari J D, Savage E P

出版信息

J Assoc Off Anal Chem. 1980 Jul;63(4):736-41.

Abstract

A method for the detection of organochlorine pesticides and polychlorinated biphenyls (PCBs) in human milk is described. The method involves quantitative extraction of human milk with acetone and hexane. The pesticide and PCB residues are extracted from the milk fat with acetonitrile (ACN) and then partitioned back into hexane by aqueous dilution of the ACN extract. The ACN partitioning is followed by cleanup with Florisil column chromatography, eluting with 6 and 15% mixtures of ethyl ether-hexane. The 6% eluate is concentrated and transferred to a silicic acid column for separation of PCBs from pesticide residues. Compounds are quantitated by gas-liquid chromatography. Recovery studies demonstrated that the procedure provides 68-103% recovery for pesticides and PCBs.

摘要

本文描述了一种检测人乳中有机氯农药和多氯联苯（PCBs）的方法。该方法包括用丙酮和己烷对人乳进行定量萃取。农药和多氯联苯残留物先用乙腈（ACN）从乳脂肪中萃取出来，然后通过对ACN萃取液进行水稀释使其重新分配到己烷中。ACN分配之后，用弗罗里硅土柱色谱法进行净化，用6%和15%的乙醚 - 己烷混合物洗脱。6%的洗脱液经浓缩后转移至硅酸柱，以从农药残留物中分离多氯联苯。化合物通过气液色谱法定量。回收率研究表明，该方法对农药和多氯联苯的回收率为68 - 103%。

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