Toama M A, Hamed I M, Ashour S M
Pharmazie. 1980;35(4):228-30.
Carbenicillin and gentamicin were tested on rats experimentally burned and infected by a selected strain of Pseudomonas aeruginosa. Carbenicillin injection was found to be the best treatment as it decreased pus formation and enhanced healing. Gentamicin was less effective than carbenicillin. The use of hydrophilic base ointment containing antibiotics is contraindicated, as it probably provides a favourable environment for Pseudomonas aeruginosa growth. The administration of supernatant vaccines and cell vaccines alone and in conjunction with the antibiotics did not modify the course of infection and healing.
用羧苄青霉素和庆大霉素对经选定的铜绿假单胞菌菌株造成实验性烧伤并感染的大鼠进行了测试。结果发现，注射羧苄青霉素是最佳治疗方法，因为它能减少脓液形成并促进愈合。庆大霉素的效果不如羧苄青霉素。含有抗生素的亲水性基质软膏的使用是禁忌的，因为它可能为铜绿假单胞菌的生长提供有利环境。单独或与抗生素联合使用上清液疫苗和细胞疫苗并没有改变感染和愈合的进程。
