Toolis F, McKay G, Prowse C V
Thromb Haemost. 1980 Feb 29;43(1):25-7.
5 severe haemophiliacs were infused with cryoprecipitate prepared by the continuous thaw-siphon technique, with cryoprecipitate prepared by overnight thawing and with intermediate-purity factor VIII concentrate. All 3 preparations gave a similar mean half-life for coagulant factor VIII of approximately 10 hours. The immediate recovery of this activity was similar for the 2 cryoprecipitates, but higher for the purified concentrate.
5名严重血友病患者分别输注了采用连续解冻虹吸技术制备的冷沉淀、过夜解冻制备的冷沉淀以及中纯度的凝血因子VIII浓缩剂。所有这三种制剂使凝血因子VIII的平均半衰期相似，约为10小时。两种冷沉淀的这种活性的即时恢复相似，但纯化浓缩剂的即时恢复更高。
