三氟胸腺嘧啶核苷治疗单纯疱疹性角膜溃疡的临床评估

Trifluorthymidine in the treatment of herpes simplex corneal ulcers. A clinical evaluation.

作者信息

Gilbert P, Work K

出版信息

Acta Ophthalmol (Copenh). 1980;58(1):117-20. doi: 10.1111/j.1755-3768.1980.tb04573.x.

DOI:10.1111/j.1755-3768.1980.tb04573.x

Abstract

The treatment of herpetic corneal ulcerations with trifluorthymidine (F3T) has been evaluated in a clinical trial. F3T was found to be an effective antiviral agent for herpetic keratitis and a valuable alternative to idoxuridine (IDU)-therapy. Clinically IDU-resistent herpetic ulcers responded favourably to treatment with F3T.

摘要

在一项临床试验中对三氟胸苷（F3T）治疗疱疹性角膜溃疡进行了评估。发现F3T是治疗疱疹性角膜炎的一种有效抗病毒药物，是碘苷（IDU）治疗的一种有价值的替代方法。临床上对IDU耐药的疱疹性溃疡对F3T治疗反应良好。