Pollitt R J, Sandhu B
J Inherit Metab Dis. 1980;3(1):17-8. doi: 10.1007/BF02312517.
Large amounts of ascorbic acid occur occasionally in the urine of children being investigated for possible inherited metabolic disease and may give a positive ninhydrin reaction after thin-layer chromatography. As this compound is unstable in urine and runs with valine in a solvent system commonly used for preliminary screening, it is a possible source of confusion.
在对可能患有遗传性代谢疾病进行检查的儿童尿液中,偶尔会出现大量的抗坏血酸,并且在薄层色谱分析后可能会给出阳性茚三酮反应。由于这种化合物在尿液中不稳定,且在常用于初步筛查的溶剂系统中与缬氨酸一起移动,它可能是造成混淆的一个原因。