躁狂症和双相抑郁症患者促甲状腺激素对促甲状腺激素释放激素的反应。
The thyroid-stimulating hormone response to thyrotropin-releasing hormone in mania and bipolar depression.
作者信息
Extein I, Pottash A L, Gold M S, Cadet J, Sweeney D R, Davies R K, Martin D M
出版信息
Psychiatry Res. 1980 May;2(2):199-204. doi: 10.1016/0165-1781(80)90077-3.
The release of thyroid-stimulating hormone (TSH) from the pituitary after infusion of 500 microgram of thyrotropin-releasing hormone (TRH) was decreased (p < 0.01) in manic patients and increased (p < 0.01) in bipolar depressed patients compared to a control group of patients with personality disorders. These results suggest that the TRH test may be useful in the diagnosis of psychiatric disorders and in the prediction of response to pharmacotherapy. We discuss the role of central monoaminergic systems in changes in the TSH response to TRH.
与人格障碍患者对照组相比，躁狂患者静脉注射500微克促甲状腺激素释放激素（TRH）后，垂体促甲状腺激素（TSH）释放减少（p<0.01），双相抑郁患者则增加（p<0.01）。这些结果表明，TRH试验可能有助于精神疾病的诊断及药物治疗反应的预测。我们讨论了中枢单胺能系统在TSH对TRH反应变化中的作用。
Zotero 插件