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安非他命后的“从这里到那里”表现:连续辨别中反应要求的重要性。

"Go here-to there" performance after amphetamine: the importance of the response requirement in successive discrimination.

作者信息

Ridley R M, Weight M L, Haystead T A, Baker H F

出版信息

Psychopharmacology (Berl). 1980;69(3):271-3. doi: 10.1007/BF00433094.

DOI:10.1007/BF00433094
PMID:6774366
Abstract

Marmosets were trained on a task involving simultaneous and successive visual discrimination performance where responses were required on all trials. Performance of this task was not affected by low doses of amphetamine. From this it is concluded that amphetamine does not cause a narrowing of attention and that the disruptive effect of amphetamine on the "go-no go" successive discrimination task already reported is due to a loss of response inhibition rather than to difficulties in the recognition of stimuli presented without a comparison stimulus.

摘要

狨猴接受了一项任务训练,该任务涉及同时性和继时性视觉辨别表现,所有试验都需要做出反应。低剂量苯丙胺对这项任务的表现没有影响。由此得出结论,苯丙胺不会导致注意力变窄,并且苯丙胺对先前报道的“去 - 不去”继时辨别任务的干扰作用是由于反应抑制的丧失,而不是由于在没有比较刺激的情况下识别呈现的刺激存在困难。

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本文引用的文献

1
Schedules using noxious stimuli. II: low intensity electric shock as a discriminative stimulus.使用有害刺激的时间表。二:低强度电击作为辨别性刺激。
J Exp Anal Behav. 1967 Jan;10(1):109-18. doi: 10.1901/jeab.1967.10-109.
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Enhancement of human performance by caffeine and the amphetamines.咖啡因和安非他明对人类机能的增强作用。
Pharmacol Rev. 1962 Mar;14:1-36.
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Amphetamine disrupts successive but not simultaneous visual discrimination in the monkey.
Psychopharmacology (Berl). 1980;67(3):241-4. doi: 10.1007/BF00431263.
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Influence of drugs on behavior controlled by internal and external stimuli.药物对由内部和外部刺激控制的行为的影响。
J Pharmacol Exp Ther. 1966 Jun;152(3):388-96.
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Effects of scopolamine, atropine, and d-amphetamine on internal and external control of responding on non-reinforced trials.东莨菪碱、阿托品和右旋苯丙胺对非强化试验中反应的内部和外部控制的影响。
Psychopharmacologia. 1970 Aug 19;18(1):38-49. doi: 10.1007/BF00402382.
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Stereotyped activities produced by amphetamine in several animal species and man.安非他命在多种动物和人类身上引发的刻板行为。
Psychopharmacologia. 1967;11(4):300-10. doi: 10.1007/BF00404607.
7
Biochemistry and behavior: some central actions of amphetamine and antipsychotic drugs.生物化学与行为:安非他明和抗精神病药物的一些核心作用
Annu Rev Psychol. 1976;27:91-127. doi: 10.1146/annurev.ps.27.020176.000515.
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Behavioural effects of amphetamine in a small primate: relative potencies of the d- and l-isomers.
Psychopharmacology (Berl). 1978 Dec 8;59(3):243-5. doi: 10.1007/BF00426628.
9
"Paradoxical" effects of psychomotor stimulant drugs in hyperactive children from the standpoint of behavioural pharmacology.从行为药理学角度看精神运动兴奋剂药物对多动症儿童的“矛盾”效应。
Neuropharmacology. 1979 Dec;18(12):931-50. doi: 10.1016/0028-3908(79)90157-6.