一名患有慢性活动性肝炎和肾小球肾炎的患者出现严重的大疱性皮疹。
A severe bullous eruption occurring in a patient with chronic active hepatitis and glomerulonephritis.
作者信息
Breathnach S M, Dutt M K, Black M M
出版信息
Arch Dermatol. 1980 Sep;116(9):1061-3.
PMID:6774668
Abstract
A patient with chronic active hepatitis and membranous glomerulonephritis acquired an acute, fatal illness characterized by a toxic erythematous desquamative dermatitis with bulla formation, fever, diarrhea, and hepatic and renal failure. The cutaneous histopathologic appearance resembled that found in erythema multiforme, toxic epidermal necrolysis, and the acute graft vs host reaction. The cutaneous eruption may have been part of a widespread atuoimmune reaction, possibly triggered by drugs or infection.
摘要
一名患有慢性活动性肝炎和膜性肾小球肾炎的患者患上了一种急性致命疾病，其特征为伴有水疱形成的中毒性红斑脱屑性皮炎、发热、腹泻以及肝肾功能衰竭。皮肤组织病理学表现类似于多形红斑、中毒性表皮坏死松解症以及急性移植物抗宿主反应中的表现。皮肤疹可能是广泛自身免疫反应的一部分，可能由药物或感染引发。
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