Dyková I, Lom J, Egusa S
Folia Parasitol (Praha). 1980;27(3):213-6.
The microsporidian Glugea plecoglossi induces in its fish host Plecoglossus altivelis a hypertrophic growth of the infected cells, resulting in formation of large xenomas. Early thin-walled xenomas did not elicit any reaction of the surrounding tissue. Later, however, coinciding with the mature xenoma being filled up with a growing mass of spores, proliferative inflammatory reaction sets in, changing gradually the xenoma into a granuloma. The granulation tissue grows into the spore mass. The spores are eliminated by macrophages and the granuloma undergoes involution. A complete functional reparation of heavily infected organs is hardly possible. Essentially, the tissue reaction was found to follow the pattern known in G. anomala infections in sticklebacks and in some other Glugea species initiating the formation of large xenomas.
微孢子虫格氏粘体虫会使其宿主鱼类香鱼的受感染细胞出现肥大性生长，从而形成大型异核体。早期薄壁异核体不会引发周围组织的任何反应。然而，后来随着成熟异核体充满不断增多的孢子团，增殖性炎症反应开始出现，逐渐将异核体转变为肉芽肿。肉芽组织长入孢子团。孢子被巨噬细胞清除，肉芽肿逐渐退化。严重感染的器官几乎不可能实现完全的功能修复。从本质上讲，组织反应遵循了在棘鱼感染异形格氏粘体虫以及其他一些引发大型异核体形成的粘体虫物种中所熟知的模式。
