[实验性肺微栓塞中的血流动力学与气体交换]
[Hemodynamics and gas exchange in experimental pulmonary microembolism].
作者信息
Simbirtsev S A, Beliakov N A, Golokhvastov N N, Dubikaĭtis A Iu, Petrash V V
出版信息
Vestn Khir Im I I Grek. 1980 Sep;125(9):104-7.
PMID:6775404
Abstract
Parameters of hemodynamics and gas exchange were studied in experiments in 25 dogs having experimental microembolism of the lungs. Microembolism was found to result in an abrupt increase of the pulmonary arterial pressure and resistance of lungs, stable hypoxemia with phenomena of metabolic acidosis, incrsed intrapulmonary shunting and the ventilation/perfusion ratio. The mechanisms of hemodynamic and respiratory rearrangement are discussed.
摘要
对25只患有实验性肺微栓塞的狗进行实验，研究其血流动力学和气体交换参数。发现微栓塞导致肺动脉压和肺阻力突然增加，伴有代谢性酸中毒现象的稳定低氧血症，肺内分流增加以及通气/灌注比增加。并讨论了血流动力学和呼吸重新调整的机制。
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