Wirsing von König C H, Finger H
Zentralbl Bakteriol A. 1980 Mar;246(2):204-10.
The influence of an infection with a sublethal dose of viable Listeria monocytogenes on the primary antibody-forming potential of mice against sheep erythrocytes (SE) was monitored by means of counting plaque-forming cells (PFC) in the spleen and measuring circulating antibodies against SE. Additionally, the course of infection was followed by determination of viable bacteria in the spleen. As against the injection of killed L. monocytogenes, infection with viable bacteria did not display any significant influence on the immune response against SE when the immunogenic stimulus was given either stimultaneously with the bacteria or on day 4 or 13 of infection, respectively. Vice versa, the immunization with the particulate antigen had no measurable influence on either course of outcome of infection with the parasite.
通过计数脾脏中的空斑形成细胞（PFC）并测量抗绵羊红细胞（SE）的循环抗体，监测亚致死剂量的活单核细胞增生李斯特菌感染对小鼠针对SE的初次抗体形成潜力的影响。此外，通过测定脾脏中的活菌来跟踪感染过程。与注射灭活的单核细胞增生李斯特菌相比，当免疫原性刺激分别与细菌同时给予或在感染的第4天或第13天时，活菌感染对针对SE的免疫反应没有显示出任何显著影响。反之亦然，用颗粒抗原进行免疫对寄生虫感染的任何一个过程或结果都没有可测量的影响。
