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[使用人抗β-促甲状腺激素抗体对猕猴(食蟹猴)腺垂体促甲状腺细胞进行免疫组织化学个体化研究]

[Immunohistochemical individualization of adenohypophyseal thyrotropic cells in the monkey Macaca irus, using a human anti-beta-TSH antibody].

作者信息

Girod C, Trouillas J

出版信息

C R Seances Acad Sci D. 1980 Sep 15;291(2):261-4.

PMID:6775838
Abstract

Using the indirect immunofluorescence technique and an antiserum against the specific beta subunit of human TSH, selective immunocytochemical staining was localized in a cell population of the pars distalis of the monkey Macaca irus. These thyrotropic cells, which were positive to aldehyde fuchsin, Alcian blue, and PAS, were localized on the one hand in the ventro-medial zone of the pars distalis, especially alongside the large vessels of this region, and on the other in the zona tuberalis, i. e. at the bottom of the pars tuberalis. Some cells, sparsely distributed, were seen in the posterior part of the lateral lobes of the pars distalis, in the vicinity of the pars intermedia. No thyrotropic cells were encountered in pars tuberalis. Pars intermedia and posterior lobe contained no cells immunoreactive to beta-hTSH. In females, the thyrotropic cells were more numerous and larger than in males. Generally the thyrotropic cells were round or oval in shape, sometimes they were polygonal.

摘要

利用间接免疫荧光技术以及针对人促甲状腺激素特异性β亚基的抗血清,在猕猴(Macaca irus)远侧部的一群细胞中实现了选择性免疫细胞化学染色定位。这些促甲状腺细胞对醛复红、阿尔辛蓝和PAS呈阳性反应,一方面位于远侧部的腹内侧区,特别是在该区域的大血管旁,另一方面位于结节部,即结节部的底部。在远侧部侧叶后部、中间部附近可见一些稀疏分布的细胞。在结节部未发现促甲状腺细胞。中间部和后叶未发现对β-hTSH有免疫反应的细胞。雌性的促甲状腺细胞比雄性的更多、更大。一般来说,促甲状腺细胞呈圆形或椭圆形,有时呈多边形。

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引用本文的文献

1
Topographical distribution of the gonadotrophs, mammotrophs, somatotrophs and thyrotrophs in the pituitary gland of the baboon (Papio cynocephalus).狒狒(Papio cynocephalus)垂体中促性腺激素细胞、催乳激素细胞、生长激素细胞和促甲状腺激素细胞的分布。
Cell Tissue Res. 1983;230(1):233-8. doi: 10.1007/BF00216044.