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对运动训练对慢性阻塞性气道疾病患者价值的客观评估。

An objective assessment of the value of exercise training to patients with chronic obstructive airways disease.

作者信息

Mungall I P, Hainsworth R

出版信息

Q J Med. 1980 Winter;49(193):77-85.

PMID:6776585
Abstract

The value of a programme of graded exercise training was assessed in ten subjects with chronic obstructive airways disease. Assessments were made at two-weekly intervals during three twelve-week periods: before, during and after a period of training. During the training the subjects were able to walk significantly further in a 12 minute walking test. There was also a small but significant increase in the forced expiratory volume in one second and the difference between the values of total lung capacity estimated by body plethysmography and those estimated by helium dilution was significantly smaller. The transfer factor for carbon monoxide increased and was significantly greater in the period after stopping the training. The difference between alveolar and arterial oxygen tensions at rest was smaller during the training period. The changes in the results of the 12 minute walking test, transfer factor and the oxygen tension difference were maintained in the period after stopping the training. Despite the improvements in some of the indices of respiratory function there were no improvements in any of the indices of cardiorespiratory fitness which may be because the subjects were incapable of undertaking sufficiently intense training. It is concluded that training is of some benefit to patients with chronic obstructive airways disease but that the benefit may be greater in patients who are less incapacitated and who are able to undertake a more strenuous training programme.

摘要

对10名慢性阻塞性气道疾病患者进行了分级运动训练计划的价值评估。在三个为期12周的阶段中,每隔两周进行一次评估:训练前、训练期间和训练后。在训练期间,受试者在12分钟步行测试中能够行走得更远。一秒用力呼气量也有小幅但显著的增加,体容积描记法估计的肺总量值与氦稀释法估计的肺总量值之间的差异显著减小。一氧化碳弥散量增加,且在停止训练后的阶段显著更大。训练期间静息时肺泡与动脉血氧分压之间的差异更小。停止训练后的阶段,12分钟步行测试结果、弥散量和氧分压差异的变化得以维持。尽管呼吸功能的一些指标有所改善,但心肺适能的任何指标均未改善,这可能是因为受试者无法进行足够强度的训练。结论是,训练对慢性阻塞性气道疾病患者有一定益处,但对于功能障碍较轻且能够进行更剧烈训练计划的患者,益处可能更大。

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