Knowles R C, Moore T D
Am J Clin Pathol. 1980 Oct;74(4 Suppl):581-5.
From 1974 through December 1978, over 180 laboratories participated in the Microbiology Program of the College of American Pathologists Quality Assurance Service (QAS), submitting a total of 2,372,000 individual antibiotic determinations on three quality control reference strains. Of these determinations, 89.5% were obtained by the standard Bauer-Kirby method; 8.4% by the agar overlay modification of Barry and associates. Standard statistical analysis of data obtained using the agar overlay modification has been reported for each antimicrobic/reference strain combination. Comparisons have been made between the QAS data and those data obtained in earlier collaborative studies, which currently serve as precision and accuracy control limits. In many cases QAS data exceed the existing control limits.
从1974年到1978年12月，超过180个实验室参与了美国病理学家学会质量保证服务（QAS）的微生物学项目，对三种质量控制参考菌株进行了总共237.2万次单独的抗生素测定。在这些测定中，89.5%是通过标准的鲍尔-柯比方法获得的；8.4%是通过巴里及其同事的琼脂覆盖改良法获得的。对于每种抗菌药物/参考菌株组合，已报告了使用琼脂覆盖改良法获得的数据的标准统计分析。已将QAS数据与早期协作研究中获得的数据进行了比较，这些数据目前用作精密度和准确度控制限。在许多情况下，QAS数据超过了现有的控制限。
