Weber M J, Hefti E, Wetz B, Kinser J
Helv Chir Acta. 1980 Jun;47(1-2):7-10.
Four to five years after the operation of an endemic goiter, 63% of the patients regularly take thyroxin prophylactically and 85% as substitution. The effect of this hormone therapy was checked using the radioiodine uptake of the thyroid. In those patients with an increase in the size of the thyroid in the scintigram, there was usually a pathological TRH-TSH test with elevated basal and very elevated late values for TSH. While the prophylactic benefit of thyroxin after unilateral thyroidectomy must be further evaluated with other parameters, there is no doubt that thyroxin is necessary for those patients in whom a bilateral thyroidectomy has been performed.
地方性甲状腺肿手术后四至五年，63%的患者定期预防性服用甲状腺素，85%的患者用于替代治疗。通过甲状腺的放射性碘摄取来检查这种激素治疗的效果。在闪烁图中甲状腺增大的患者中，通常会有TRH-TSH试验异常，基础促甲状腺激素（TSH）值升高，后期值大幅升高。虽然单侧甲状腺切除术后甲状腺素的预防益处必须用其他参数进一步评估，但对于那些接受双侧甲状腺切除术的患者来说，甲状腺素是必不可少的，这一点毫无疑问。
