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小鼠颌下腺对雄激素和甲状腺激素反应性的发育

Development of responsiveness of mouse submandibular gland to androgen and thyroid hormone.

作者信息

Takuma T, Hosoda S, Tanemura T, Kumegawa M

出版信息

J Dent Res. 1981 Jan;60(1):77-9. doi: 10.1177/00220345810600011501.

Abstract

The effects of thyroxine and 5 alpha-dihydrotestosterone on the activities of various marker enzymes in the submandibular glands of immature mice were studied. The responsiveness to thyroid hormone appeared at latest by day five after birth, which was ten d earlier than the appearance of androgen responsiveness. The activity of trypsin-like esteroprotease, however, was not increased by these hormones until day 15 after birth.

摘要

研究了甲状腺素和5α-双氢睾酮对未成熟小鼠颌下腺中各种标志酶活性的影响。对甲状腺激素的反应最晚在出生后第5天出现,这比雄激素反应的出现早10天。然而,直到出生后第15天,这些激素才使胰蛋白酶样酯蛋白酶的活性增加。

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