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肺切除术后的心脏紊乱——预防性洋地黄化的价值

Cardiac disturbances after pneumonectomy--the value of prophylactic digitalization.

作者信息

Järvinen A, Mattila T, Appelqvist P, Meurala H, Mattila S

出版信息

Ann Chir Gynaecol. 1978;67(2):77-81.

PMID:677777
Abstract

The incidence of postoperative cardiac disturbances and the value of prophylactic digitalization were studied retrospectively in 143 patients undergoing pneumonectomy for carcinoma of the lung. Cardiac arrhythmias occurred in 29% and tachycardia episodes in 30% of the patients. The incidence of myocardial infarction was 2%. Operative mortality was 4%. The cardiac disturbances developed more often after left than after right pneumonectomy. The age of the patients, a history of angina pectoris or hypertension did not markedly increase the incidence of cardiac disturbances, neither did operative factors, such as pericardiotomy, left atrial resection, major bleeding nor postoperative empyema. Prophylactic digitalization significantly reduced postoperative cardiac disorders, their frequency being 33% in the group of patients who received prophylactic digitalis compared with 65% in the group that did not.

摘要

对143例因肺癌行肺切除术的患者进行回顾性研究,分析术后心脏功能紊乱的发生率及预防性洋地黄化的价值。心律失常发生率为29%,心动过速发作发生率为30%。心肌梗死发生率为2%。手术死亡率为4%。心脏功能紊乱在左肺切除术后比右肺切除术后更常发生。患者年龄、心绞痛或高血压病史并未显著增加心脏功能紊乱的发生率,心包切开术、左心房切除术、大出血及术后脓胸等手术因素也未增加其发生率。预防性洋地黄化显著降低了术后心脏疾病的发生率,接受预防性洋地黄治疗的患者组发生率为33%,未接受治疗的患者组为65%。

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