Adami H O, Vegelius J
Ann Clin Res. 1978 Feb;10(1):38-42.
Several methods have been suggested for estimating the error introduced into epidemiological investigations by potential participants who decline participation. As these could not be applied to our present epidemiological case-control breast cancer study, a new and simple method was developed based on information gathered from those controls who participated only relunctantly. A formula is given for calculating an adjusted mean for the sample and corresponding p-value. Our own data were used to illustrate the method. The calculations then indicated that those who declined participation were slightly selected in some aspects, but not to such a degree as to obscure or cause any significant differences between patient and control groups.
已经提出了几种方法来估计拒绝参与的潜在参与者给流行病学调查带来的误差。由于这些方法不适用于我们目前的乳腺癌病例对照流行病学研究，因此基于从那些勉强参与的对照者收集的信息开发了一种新的简单方法。给出了一个计算样本调整均值和相应p值的公式。我们自己的数据用于说明该方法。计算结果表明，拒绝参与的人在某些方面略有选择性，但程度不至于掩盖或导致患者组和对照组之间出现任何显著差异。
