Ovenfors C O, Dahlgren S E, Ripe E, Ost A
AJR Am J Roentgenol. 1980 Oct;135(4):703-12. doi: 10.2214/ajr.135.4.703.
The clinical, radiographic, and histopathologic characteristics of pulmonary muscular hyperplasia were analyzed in 13 patients who were seen over a 13 year period. The average follow-up period was 7.2 years (range, 1-13). Eight patients initially demonstrated interstitial disease radiographically and the radiographic diagnosis was "interstitial fibrosis." The radiographs of the other five patients exhibited only localized infiltrates initially--produced by bronchiectasis in three, inflammatory mass in one, and bronchial carcinoma in one. Histologic features were consistent with desquamative interstitial pneumonia in eight, usual interstitial pneumonia in one, and unspecified interstitial pneumonia in four. When tuberous sclerosis is absent, pulmonary muscular hyperplasia is probably an end stage of interstitial pneumonia.
对13年间诊治的13例肺肌增生患者的临床、影像学和组织病理学特征进行了分析。平均随访期为7.2年（范围1 - 13年）。8例患者最初影像学表现为间质性疾病，影像学诊断为“间质性纤维化”。另外5例患者最初的X线片仅显示局限性浸润——3例由支气管扩张引起，1例由炎性肿块引起，1例由支气管癌引起。组织学特征8例符合脱屑性间质性肺炎，1例符合普通间质性肺炎，4例符合未分类的间质性肺炎。当不存在结节性硬化时，肺肌增生可能是间质性肺炎的终末期表现。
