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[口服避孕药与冠状动脉血栓形成。两例临床病理病例]

[Oral contraceptive and coronary thrombosis. Two clinicopathological cases].

作者信息

Loire R, Touboul P, Gressard A, Rondepierre D, Tabib A

出版信息

Arch Mal Coeur Vaiss. 1980 Apr;73(4):432-7.

PMID:6778445
Abstract

The cases reported are interesting from two points of view: they confirm the thrombotic mechanism of the arteria lesions (coronary amongst others) and the oral contraception pill was the only cardiovascular risk factor, smoking, hyperlipidaemia, hypertension and coronary atherosclerosis having been eliminated. The two young women (31 and 34 years old) presented with severe myocardial infarction and shock, leading to death within hours in one case and within weeks in the other (despite an attempt to resect the infarct and prolonged intraaortic balloon pumping). In both cases multiple thromboses were discovered: coronary, intra cardiac and in the collateral aortic circulation.

摘要

从两个角度来看,所报告的病例很有意思:它们证实了动脉病变(尤其是冠状动脉病变)的血栓形成机制,并且口服避孕药是唯一的心血管危险因素,吸烟、高脂血症、高血压和冠状动脉粥样硬化已被排除。两名年轻女性(分别为31岁和34岁)出现严重心肌梗死和休克,其中一例在数小时内死亡,另一例在数周内死亡(尽管尝试切除梗死灶并延长主动脉内球囊反搏)。在这两个病例中均发现多处血栓形成:冠状动脉、心脏内以及主动脉侧支循环。

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[Combined contraceptives and cardiovascular risk].[复方避孕药与心血管风险]
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