Shead G, Shah S G
Aust N Z J Surg. 1980 Oct;50(5):459-62. doi: 10.1111/j.1445-2197.1980.tb04168.x.
A series of 85 patients with carcinoma of the pancreas seen in South India has been analysed. The median age was 50 years, 20% of patients being below years of age, and the male to female ratio was 4:1. Diabetes mellitus and smoking were more prevalent among males than in a control group, but this was not the case with alcoholism. Distribution of blood groups was the same as in controls. Clinical features of these patients are reviewed. Operative mortality in jaundiced patients was similar whether simple laparotomy, a biliary bypass procedure or a pancreaticoduodectomy was done. This mortality was related to the depth of jaundice and to the degree of abnormality in serum transaminase levels, but it was not related to the age of the patient, the stage of the disease, ECG evidence of ischaemic heart disease, or abnormalities in either serum albumin concentration or blood urea level. Following biliary bypass procedures 50% of patients were dead within eight months; after pancreatoduodenectomy this interval was increased to 18 months, but differences in the stage of the disease between the two groups would account for the difference in survival to some extent.
对在印度南部收治的85例胰腺癌患者进行了分析。中位年龄为50岁，20%的患者年龄低于该年龄，男女比例为4:1。糖尿病和吸烟在男性中比在对照组中更普遍，但酗酒情况并非如此。血型分布与对照组相同。对这些患者的临床特征进行了回顾。无论进行单纯剖腹手术、胆道旁路手术还是胰十二指肠切除术，黄疸患者的手术死亡率相似。该死亡率与黄疸深度和血清转氨酶水平异常程度有关，但与患者年龄、疾病分期、缺血性心脏病的心电图证据或血清白蛋白浓度或血尿素水平异常无关。胆道旁路手术后，50%的患者在八个月内死亡；胰十二指肠切除术后，这个间隔延长至18个月，但两组疾病分期的差异在一定程度上解释了生存差异。
