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[吸入抗菌制剂治疗对肺结核患者呼吸道真菌-酵母样菌群的影响]

[Effect of inhalatory therapy with antibacterial preparations on the fungal-yeastlike flora of the respiratory tracts in pulmonary tuberculosis].

作者信息

Kulik N M, Iatsozhinskiĭ Iu D

出版信息

Antibiotiki. 1978 Jul;23(7):642-4.

PMID:677856
Abstract

A total of 254 patients with various forms of the lung tuberculosis were examined on the presence of the yeast-like flora; 130 patients out of them (the main group) were subjected to complex antibacterial therapy including inhalation with antitubercle drugs and 124 patients (control) were not treated with inhalation. On acceptance to the stationary the fungal flora was registered in 22.4% of the patients including 20.9% of the males and 29.2% of the females. The fungi were found more often in old patients (33.3%), patients with diseases of long duration (29.7%) and patients with fibrous cavernous tuberculosis of the lungs (27.1%). It was shown that the local treatment of the patients suffering from the lung tuberculosis with antitubercle drugs including streptomycin had no significant effect on either the period of the fungi carrying (22.3% before the treatment and 21.5% after the treatment, P less than 0.05), or development of the fungal diseases (1.9% in the main group and 1.6% in the control group, P greater than 0.05).

摘要

对总共254例患有各种类型肺结核的患者进行了酵母样菌群检查;其中130例患者(主要组)接受了包括抗结核药物吸入在内的综合抗菌治疗,124例患者(对照组)未接受吸入治疗。入院时,22.4%的患者检测出真菌菌群,其中男性为20.9%,女性为29.2%。真菌在老年患者(33.3%)、病程较长的患者(29.7%)和肺部纤维空洞性结核患者(27.1%)中更为常见。结果表明,用包括链霉素在内的抗结核药物对肺结核患者进行局部治疗,对真菌携带期(治疗前为22.3%,治疗后为21.5%,P<0.05)或真菌疾病的发生(主要组为1.9%,对照组为1.6%,P>0.05)均无显著影响。

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