Schläppi B, Jenni L
Acta Trop. 1977 Mar;34(1):43-51.
Antigenic variants of T. congolense transmitted by G. m. morsitans through normal and X-irradiated mice were investigated by means of the neutralization test and IFAT. Clones of a cyclically passaged derivative strain were isolated from irradiated and normal mice. The IFAT revealed cross immunofluorescent reactions between most of the stabilates, whereas only the two clones obtained from irradiated mice were totally neutralized by their homologous antisera. These two antisera showed no cross neutralizing activity. The results indicate a possible antigenic heterogeneity of the extruded metacyclic forms.
通过中和试验和间接荧光抗体试验（IFAT），研究了冈比亚须舌蝇（Glossina morsitans morsitans）通过正常和X射线照射小鼠传播的刚果锥虫（Trypanosoma congolense）的抗原变异体。从经照射和正常的小鼠中分离出了一个循环传代衍生菌株的克隆。间接荧光抗体试验显示，大多数稳定期培养物之间存在交叉免疫荧光反应，而仅从经照射小鼠获得的两个克隆被其同源抗血清完全中和。这两种抗血清没有交叉中和活性。结果表明，循环后期锥鞭毛体可能存在抗原异质性。
