阿米替林或去甲替林治疗的人类受试者血浆中孵育的血小板和突触体对5-羟色胺和去甲肾上腺素摄取的抑制作用：生物测定方法原理的应用 - Suppr

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超能文献

Inhibition of 5-hydroxytryptamine and noradrenaline uptake in platelets and synaptosomes incubated in plasma from human subjects treated with amitryptyline or nortriptyline: utilization of the principle for a bioassay method.

作者信息

Tuomisto J, Tukiainen E, Voutilainen R, Tuomainen P

出版信息

Psychopharmacology (Berl). 1980;69(2):137-42. doi: 10.1007/BF00427639.

DOI:10.1007/BF00427639

PMID:6779306

Abstract

摘要

相似文献

Inhibition of 5-hydroxytryptamine and noradrenaline uptake in platelets and synaptosomes incubated in plasma from human subjects treated with amitryptyline or nortriptyline: utilization of the principle for a bioassay method.阿米替林或去甲替林治疗的人类受试者血浆中孵育的血小板和突触体对5-羟色胺和去甲肾上腺素摄取的抑制作用：生物测定方法原理的应用

Psychopharmacology (Berl). 1980;69(2):137-42. doi: 10.1007/BF00427639.

Effects of 4-(3-indolyl-alkyl)piperidine derivatives on uptake and release of noradrenaline, dopamine and 5-hydroxytryptamine in rat brain synaptosomes, rat heart and human blood platelets.4-（3-吲哚基-烷基）哌啶衍生物对大鼠脑突触体、大鼠心脏和人血小板中去甲肾上腺素、多巴胺和5-羟色胺摄取与释放的影响。

Biochem Pharmacol. 1977 Mar 15;26(6):497-503. doi: 10.1016/0006-2952(77)90324-0.

Tricyclic antidepressant agents. I. Comparison of the inhibition of the uptake of 3-H-noradrenaline and 14-C-5-hydroxytryptamine in slices and crude synaptosome preparations of the midbrain-hypothalamus region of the rat brain.三环类抗抑郁药。I. 大鼠脑下丘脑-中脑区域切片和粗制突触体制剂中3-H-去甲肾上腺素和14-C-5-羟色胺摄取抑制作用的比较。

Acta Pharmacol Toxicol (Copenh). 1975;36(Suppl 5):382-94. doi: 10.1111/j.1600-0773.1975.tb00806.x.

Uptake of serotonin into rat platelets and synaptosomes: comparative structure-activity relationships, energetics and evaluation of the effects of acute and chronic nortriptyline administration.血清素在大鼠血小板和突触体中的摄取：比较结构-活性关系、能量学以及急性和慢性给予去甲替林的效果评估。

Brain Res Bull. 1986 Jul;17(1):67-73. doi: 10.1016/0361-9230(86)90162-0.

Neuropharmacological properties of amitriptyline, nortriptyline and their metabolites.

Acta Pharmacol Toxicol (Copenh). 1980 Jul;47(1):53-7. doi: 10.1111/j.1600-0773.1980.tb02025.x.

A new modification for studying 5-HT uptake by blood platelets: a re-evaluation of tricyclic antidepressants as uptake inhibitors.一种研究血小板对5-羟色胺摄取的新改良方法：三环类抗抑郁药作为摄取抑制剂的重新评估。

J Pharm Pharmacol. 1974 Feb;26(2):92-100. doi: 10.1111/j.2042-7158.1974.tb09231.x.

Effects of clomipramine and other tricyclic antidepressants on biogenic amine uptake and turnover.氯米帕明及其他三环类抗抑郁药对生物胺摄取及代谢的影响。

Postgrad Med J. 1976;52(3 suppl):33-9.

A comparison of the inhibitory effects of new non-tricyclic amine uptake inhibitors on the uptake of norepinephrine and 5-hydroxytryptamine into synaptosomes of the rat brain.新型非三环胺摄取抑制剂对去甲肾上腺素和5-羟色胺摄取到大鼠脑突触体中的抑制作用比较。

Neuropharmacology. 1980 Apr;19(4):349-54. doi: 10.1016/0028-3908(80)90186-0.

Differential binding of antidepressants to noradrenaline and serotonin transport sites in central nerve endings.抗抑郁药与中枢神经末梢去甲肾上腺素和5-羟色胺转运位点的差异性结合。

Eur J Pharmacol. 1979 Aug 15;57(4):407-16. doi: 10.1016/0014-2999(79)90503-x.

Metaraminol uptake by human thrombocytes: a poor model for neuronal noradrenaline uptake.间羟胺被人血小板摄取：一种欠佳的神经元去甲肾上腺素摄取模型。

Experientia. 1977 Oct 15;33(10):1354-5. doi: 10.1007/BF01920177.

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Imipramine Accelerates Nonalcoholic Fatty Liver Disease, Renal Impairment, Diabetic Retinopathy, Insulin Resistance, and Urinary Chromium Loss in Obese Mice.丙咪嗪会加速肥胖小鼠的非酒精性脂肪性肝病、肾损伤、糖尿病视网膜病变、胰岛素抵抗以及尿铬流失。

Vet Sci. 2021 Sep 9;8(9):189. doi: 10.3390/vetsci8090189.

Effects of zimeldine, mianserin and amitriptyline on psychomotor skills and their interaction with ethanol a placebo controlled cross-over study.

Eur J Clin Pharmacol. 1984;27(2):181-9. doi: 10.1007/BF00544043.

Inhibitors of serotonin and noradrenaline uptake in human plasma after withdrawal of zimelidine and clomipramine treatment.

Psychopharmacology (Berl). 1983;79(4):298-303. doi: 10.1007/BF00433405.

Platelets and biogenic amines. 2. Indications for a discrete low affinity uptake mechanism shared by norepinephrine and 5-hydroxytryptamine in human platelets.血小板与生物胺。2. 人类血小板中去甲肾上腺素和5-羟色胺共享的离散低亲和力摄取机制的指征。

Psychopharmacology (Berl). 1986;90(3):384-9. doi: 10.1007/BF00179196.

Serotonin uptake inhibition during treatment of depression with nortriptyline caused by parent drug and not by 10-hydroxymetabolites.用去甲替林治疗抑郁症期间的5-羟色胺摄取抑制是由母体药物引起的，而非10-羟基代谢物所致。

Psychopharmacology (Berl). 1987;92(2):169-72. doi: 10.1007/BF00177910.

Effect on radiolabelled-monoamine uptake in vitro of plasma taken from healthy volunteers administered the antidepressant sibutramine HCl.

Psychopharmacology (Berl). 1990;100(3):345-9. doi: 10.1007/BF02244604.

本文引用的文献

The uptake of adrenaline and noradrenaline by blood platelets of the pig.猪血小板对肾上腺素和去甲肾上腺素的摄取。

Br J Pharmacol Chemother. 1958 Dec;13(4):411-4. doi: 10.1111/j.1476-5381.1958.tb00230.x.

Gas chromatography-mass spectrometry of nortriptyline in body fluids of man.人体体液中去甲替林的气相色谱-质谱分析

Clin Pharmacol Ther. 1971 May-Jun;12(3):496-505. doi: 10.1002/cpt1971123496.

The role of plasma protein binding in the inhibitory effect of nortriptyline on the neuronal uptake of norepinephrine.血浆蛋白结合在去甲替林对去甲肾上腺素神经元摄取抑制作用中的作用。

Clin Pharmacol Ther. 1970 Jul-Aug;11(4):581-8. doi: 10.1002/cpt1970114581.

Plasma nortriptyline and clinical response.血浆去甲替林与临床反应。

Clin Pharmacol Ther. 1974 Oct;16(4):639-44. doi: 10.1002/cpt1974164639.

The human platelet as a pharmacologic model for the adrenergic neuron. The uptake and release of norepinephrine.人类血小板作为肾上腺素能神经元的药理学模型。去甲肾上腺素的摄取与释放。

Clin Pharmacol Ther. 1969 Sep-Oct;10(5):702-9. doi: 10.1002/cpt1969105702.

Inhibition of biogenic amines uptake by imipramine, desipramine, 2 OH-imipramine and 2 OH-desipramine in rat brain.丙咪嗪、地昔帕明、2-羟基丙咪嗪和2-羟基地昔帕明对大鼠脑内生物胺摄取的抑制作用。

Life Sci. 1979 Jan 1;24(1):21-8. doi: 10.1016/0024-3205(79)90275-3.

5-Hydroxytryptamine and dopamine transport by rat and human blood platelets.大鼠和人血小板对5-羟色胺和多巴胺的转运

Br J Pharmacol. 1978 Feb;62(2):219-26. doi: 10.1111/j.1476-5381.1978.tb08449.x.

No circadian effect on nortriptyline kinetics in man.人体中去甲替林动力学不存在昼夜节律效应。

Clin Pharmacol Ther. 1978 Feb;23(2):199-203. doi: 10.1002/cpt1978232199.

The accumulation of dopamine into striatal synaptosomes, and its inhibition: comparison of crude, partially purified and purified synaptosomal preparations.多巴胺在纹状体突触体中的积累及其抑制作用：粗制、部分纯化和纯化的突触体制剂的比较。

Med Biol. 1979 Aug;57(4):238-45.

Hydroxylated metabolites of tricyclic antidepressants: preclinical assessment of activity.三环类抗抑郁药的羟基化代谢产物：活性的临床前评估

Biol Psychiatry. 1979 Aug;14(4):601-13.

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