猪血小板对肾上腺素和去甲肾上腺素的摄取。
The uptake of adrenaline and noradrenaline by blood platelets of the pig.
作者信息
BORN G V, HORNYKIEWICZ O, STAFFORD A
出版信息
Br J Pharmacol Chemother. 1958 Dec;13(4):411-4. doi: 10.1111/j.1476-5381.1958.tb00230.x.
Abstract
Pig platelets contained 0.2 to 2.6 ng. adrenaline/10(8) platelets (4 experiments). Noradrenaline was not detected in them. When platelet-rich plasma was incubated at 37 degrees with 1 or 10mug. of added catechol amine/ml., the platelets continued to accumulate adrenaline for at least 120 min.; only about one-third as much noradrenaline as adrenaline was taken up. The concentrations of adrenaline taken up by different platelet samples at the end of incubation for 90 min. were proportional to the concentration of adenosine triphosphate in the platelets.
摘要
猪血小板含有0.2至2.6纳克肾上腺素/10⁸个血小板（4次实验）。未在其中检测到去甲肾上腺素。当富含血小板的血浆在37℃下与1或10微克/毫升添加的儿茶酚胺一起孵育时，血小板会持续积累肾上腺素至少120分钟；摄取的去甲肾上腺素仅约为肾上腺素的三分之一。孵育90分钟结束时，不同血小板样本摄取的肾上腺素浓度与血小板中三磷酸腺苷的浓度成正比。
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