Kuribara H
Psychopharmacology (Berl). 1980;71(1):105-7. doi: 10.1007/BF00433263.
The effects of repeated administration of d-amphetamine (0.5 mg/kg SC) on Sidman avoidance responding in rats were investigated. The response (lever-pressing) enhancing effect of d-amphetamine increased progressively after repeated administration. The change in behavior was more marked in the animals exposed to the avoidance situation during the period of the drug effect than in those given the drug after termination of each avoidance session. The present results suggest that the enhancing effect of d-amphetamine as demonstrated on Sidman avoidance responding in rats is dependent on the drug experience of the experimental animals and on the experimental situation to which the animals are exposed during the period of the drug effect.
研究了重复给予大鼠d-苯丙胺（0.5毫克/千克，皮下注射）对斯德曼回避反应的影响。重复给药后，d-苯丙胺的反应（按压杠杆）增强作用逐渐增加。与在每次回避训练结束后给药的动物相比，在药物作用期间暴露于回避情境的动物行为变化更为明显。目前的结果表明，d-苯丙胺对大鼠斯德曼回避反应的增强作用取决于实验动物的药物体验以及动物在药物作用期间所暴露的实验情境。
