Mitchell M R, Martin A R
Q J Exp Physiol Cogn Med Sci. 1980 Oct;65(4):309-20. doi: 10.1113/expphysiol.1980.sp002519.
The ionophore A23187 produces a hyperpolarization of cockroach salivary gland cells in the presence or absence of added calcium ions. The effect is greater and more prolonged in the presence of calcium and is dependent on the external potassium ion concentration. It is proposed that the ionophore can increase the intracellular calcium ion concentration by an increase in influx from the external medium or by mobilization of intracellular calcium stores and that this results in an increase in the potassim permeability, thus producing a hyperpolarization.
离子载体A23187在添加或未添加钙离子的情况下均可使蟑螂唾液腺细胞发生超极化。在有钙离子存在时，这种效应更强且持续时间更长，并且依赖于细胞外钾离子浓度。有人提出，该离子载体可通过增加从细胞外液的流入或通过动员细胞内钙储备来提高细胞内钙离子浓度，而这会导致钾离子通透性增加，从而产生超极化。
