Bopp P, Bloch A, Fournet P C, Mievis E, Mérier G
Arch Mal Coeur Vaiss. 1980;73(3):260-7.
The diastolic thickness of the interventricular septum was measured by echocardiography and by biventricular angiography in 48 patients (40 male, 8 female) with age ranging between 15 and 67 years (average 44.4 years). These patients were classified in four groups according to clinical and paraclinical parameters:--normal subjects (29 cases),--patients with concentric hypertrophy (5 cases),--patients with asymmetrical septal hypertrophy without obstruction (4 cases),--patients with hypertrophic cardiomyopathy with obstruction under basal conditions or under stress (10 cases). Biventricular cineangiography was performed in 70 degrees left anterior oblique projection after measuring the intracavitary pressures. Analysis was performed by projecting the film and reproducing one or several diastolic frames on paper. Septal thickness was measured at the two levels suggested by Redwood. The septum was then divided into 5 parts and the thickness measured at the corresponding 4 levels. The values obtained were then corrected for magnification artefact. Qualitative comparison of the results obtained by echocardiography and angiocardiography showed a good correlation in 35 cases (73%) and less significant correlations in the other 13 cases (27%). The poorest correlations were observed in the groups of patients with concentric or asymmetrical hypertrophy without obstruction. Of these 13 cases, angiography confirmed the clinical diagnosis in 6 cases. In the remaining 2 cases, echocardiography and angiocardiography gave divergent diagnoses which also differed from the clinical diagnosis. The quantitative correlations between the echocardiographical and angiocardiographic measurements of diastolic septal thickness were quite satisfactory in most patients. The correlation improved when the echocardiographical measurement was compared to an average of the 4 angiographical measurements; (R = 0,74; p < 0.001). The correlation was poorer in groups 2 and 3 in patients with concentric or asymmetrical hypertrophy without obstruction. The disadvantages and limitations of these two methods are discussed. Possible ambiguity in the identification of segments of the septum measured by the two methods may be a significant factor especially in cases of asymmetrical hypertrophy.
采用超声心动图和双心室血管造影术测量了48例患者(40例男性,8例女性)的室间隔舒张期厚度,患者年龄在15至67岁之间(平均44.4岁)。根据临床和辅助检查参数,将这些患者分为四组:——正常受试者(29例),——同心性肥厚患者(5例),——非梗阻性不对称性室间隔肥厚患者(4例),——基础状态或应激状态下有梗阻的肥厚型心肌病患者(10例)。在测量心腔内压力后,于左前斜70度进行双心室电影血管造影。通过放映胶片并在纸上复制一个或几个舒张期图像进行分析。按照雷德伍德建议的两个层面测量室间隔厚度。然后将室间隔分为5部分,并在相应的4个层面测量厚度。随后对获得的值进行放大假象校正。超声心动图和心血管造影所获结果的定性比较显示,35例(73%)相关性良好,另外13例(27%)相关性较弱。在同心性或非梗阻性不对称性肥厚患者组中观察到的相关性最差。在这13例中,血管造影在6例中证实了临床诊断。在其余2例中,超声心动图和血管造影给出了不同的诊断结果,且与临床诊断也不同。大多数患者舒张期室间隔厚度的超声心动图测量值与血管造影测量值之间的定量相关性相当令人满意。当将超声心动图测量值与4次血管造影测量值的平均值进行比较时,相关性有所改善;(R = 0.74;p < 0.001)。在同心性或非梗阻性不对称性肥厚患者的第2组和第3组中相关性较差。讨论了这两种方法的缺点和局限性。两种方法测量室间隔节段时可能存在的模糊性可能是一个重要因素,尤其是在不对称性肥厚的情况下。