Jakoniuk P, Borowski J, Jabłońska-Strynkowska W
Arch Immunol Ther Exp (Warsz). 1980;28(4):611-8.
The administration of Listeria monocytogenes lipids (LML) in mice resulted in the development of population of macrophages with increased phagocytic and microbicidal activity, as well as higher content of the lysosomal acid hydrolases. The elevation of the serum level of lysozyme, complement and properdin in guinea pigs after LML injection was observed. The normal macrophages cultured in vitro were also activated by LML independently on the presence or absence of autologous lymphocyte. It is concluded that the mechanism of the increase of the host resistance evoked by LML depends on the direct stimulatory effect of LML on the activity of the mononuclear phagocyte system.
给小鼠注射单核细胞增生李斯特菌脂质（LML）后，可使巨噬细胞群体发育，其吞噬和杀菌活性增强，溶酶体酸性水解酶含量也更高。观察到给豚鼠注射LML后，其血清溶菌酶、补体和备解素水平升高。体外培养的正常巨噬细胞也可被LML激活，无论是否存在自体淋巴细胞。得出的结论是，LML引起宿主抵抗力增强的机制取决于LML对单核吞噬细胞系统活性的直接刺激作用。
