Remuzzi G, Zoja C, Marchesi D, Schieppati A, Mecca G, Misiani R, Donati M B, de Gaetano G
Br Med J (Clin Res Ed). 1981 Feb 14;282(6263):512-4. doi: 10.1136/bmj.282.6263.512.
Activity of prostacyclin-stimulating factor was measured in six normal, non-pregnant women, six women in early normal pregnancy, six in late normal pregnancy, and six in late pregnancy complicated by severe pre-eclampsia. The activity was lower in the women in late pregnancy than in those in early pregnancy and the controls but was about normal in those with severe pre-eclampsia. These results may be relevant to the physiology of pregnancy and the pathogenesis of pre-eclampsia.
在六名正常未孕女性、六名正常早孕女性、六名正常晚孕女性以及六名并发严重先兆子痫的晚孕女性中测量了前列环素刺激因子的活性。晚孕女性的活性低于早孕女性和对照组,但并发严重先兆子痫的女性活性约为正常。这些结果可能与妊娠生理及先兆子痫的发病机制相关。