Remuzzi G, Marchesi D, Zoja C, Muratore D, Mecca G, Misiani R, Rossi E, Barbato M, Capetta P, Donati M B, de Gaetano G
Prostaglandins. 1980 Jul;20(1):105-10. doi: 10.1016/0090-6980(80)90010-6.
Prostacyclin production was significantly depressed in foetal and placental vascular tissues from five patients with severe pre-eclampsia in comparison to vascular tissues from women with uncomplicated pregnancy. Such an abnormality may be responsible for a reduced blood flow and defective fetal nutrition thus playing a major role in the pathogenesis of this syndrome.
与正常妊娠女性的血管组织相比，五名重度子痫前期患者的胎儿和胎盘血管组织中前列环素的生成显著降低。这种异常可能导致血流减少和胎儿营养缺陷，从而在该综合征的发病机制中起主要作用。
