Malone J I, Brodsky S J
Diabetes Care. 1980 Jul-Aug;3(4):543-7. doi: 10.2337/diacare.3.4.543.
Electrolyte abnormalities cause fatal cardiac arrhythmias in patients with diabetic ketoacidosis. A patient is reported with electrocardiogram (ECG) abnormalities characteristic of toxic hyperkalemia and hypocalcemia. The ECG abnormalities were noted during the first hour after arriving at the hospital. The laboratory values confirming the electrolyte abnormalities were not available for more than 1 h after the ECG indicated the danger of myocardial toxicity. During the initial 2 h of therapy the patient was urinating and not in shock. ECG monitoring of this patient prevented the routine administration of intravenous potassium, which was potentially lethal. The clinical importance of electrolyte levels in the management of diabetic ketoacidosis is the prevention of cardiac arrhythmias. ECG monitoring should be a minimal standard in the management of diabetic ketoacidosis.
电解质异常可导致糖尿病酮症酸中毒患者发生致命性心律失常。本文报告了一名患者,其心电图(ECG)表现出高钾血症和低钙血症中毒的特征。这些心电图异常在患者入院后的第一小时内就被发现。在心电图提示存在心肌毒性危险后1小时以上,实验室检查结果才证实了电解质异常。在治疗的最初2小时内,患者有排尿且未休克。对该患者进行心电图监测避免了常规静脉补钾,而常规补钾可能是致命的。在糖尿病酮症酸中毒的治疗中,电解质水平的临床重要性在于预防心律失常。心电图监测应成为糖尿病酮症酸中毒治疗的最低标准。