Harrower A D, Campbell I W, Ewing D J, Murray A, Neilson J M, Clarke B F
Acta Diabetol Lat. 1978 Jan-Apr;15(1-2):88-94. doi: 10.1007/BF02581011.
In order to confirm or refute the previously held view that electrocardiographic (ECG) abnormalities are frequent in diabetic ketoacidosis, we have undertaken continuous ECG monitoring for 24 h, with subsequent computer analysis, in 14 diabetic patients admitted with severe ketoacidosis. There was a steady fall in heart rate during the 24-h except in 3 severely dehydrated patients. Depression of the ST-segment was minimal and ST-segment height correlated significantly with heart rate, whereas no consistent relationship was found between T-wave amplitude and either heart rate or plasma potassium. Two patients developed short periods of supraventricular ectopic beats. Although ECG monitoring has been claimed to be a useful aid in the management of diabetic ketoacidosis, this study clearly demonstrates that significant ECG changes are rare and ECG monitoring thereafter adds little to careful clinical observation and regular biochemical assessment.
为了证实或反驳先前认为糖尿病酮症酸中毒患者经常出现心电图(ECG)异常的观点,我们对14例因严重酮症酸中毒入院的糖尿病患者进行了24小时连续心电图监测,并随后进行了计算机分析。除3例严重脱水患者外,24小时内心率持续下降。ST段压低轻微,ST段高度与心率显著相关,而T波振幅与心率或血浆钾之间未发现一致的关系。2例患者出现短时间的室上性异位搏动。尽管有人声称心电图监测有助于糖尿病酮症酸中毒的治疗,但本研究清楚地表明,明显的心电图变化很少见,因此心电图监测对仔细的临床观察和定期生化评估作用不大。