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银屑病与人类生长激素之间的关系(作者译)

[Relationship between psoriasis and human growth hormone (author's transl)].

作者信息

Weber G, Neidhardt M

出版信息

MMW Munch Med Wochenschr. 1980 Nov 21;122(47):1690-4.

PMID:6780866
Abstract

The behavior of the capillary bed, increased epidermopoiesis, increased total metabolism of psoriasis efflorescence and its first manifestation, principally in the second decade of life, drew our attention to the behavior of the human growth hormone. A rise in the serum level of the human growth hormone compared with the normal (40 control subjects) significantly correlating with the extent of the skin symptoms, acuteness and therapy was established in the serum by diurnal determination in 70 psoriasis patients. According to this, psoriasis is the etiological consequence of hereditary persistence of production of the human growth hormone with individual penetrance.

摘要

毛细血管床的行为、表皮生成增加、银屑病皮疹期总代谢增加及其主要在生命第二个十年出现的首发表现,使我们关注到人生长激素的行为。通过对70例银屑病患者进行血清昼夜测定发现,与正常情况(40名对照受试者)相比,人生长激素血清水平升高与皮肤症状的程度、严重程度及治疗情况显著相关。据此,银屑病是人生长激素分泌遗传性持续存在且具有个体外显率的病因学后果。

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