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[生长激素与银屑病病因学的相关性]

[Correlation of growth hormone and aetiology of psoriasis].

作者信息

Weber G, Neidhardt M, Schmidt A, Geiger A

出版信息

Arch Dermatol Res. 1981;270(2):129-40. doi: 10.1007/BF00408223.

Abstract

Pathological alterations of capillaries, accelerated epidermopoesis, increased rate and extent of metabolism in the psoriatic lesion and first manifestation of psoriasis rarely in the first 20 years of life made us decide to investigate the human growth hormone (STH) in blood serum. In 70 patients suffering from psoriasis we found that the extention of skin lesions was correlated to the STH levels, which were determined every 2 h all over the day. The average STH level in psoriasis was three times as high as average value in the group of 40 controls. Thus, one can conclude that psoriasis is caused by a persistence of STH with individual penetrance.

摘要

毛细血管的病理改变、表皮生成加速、银屑病皮损处代谢速率和程度增加以及银屑病极少在生命的头20年出现首发症状,促使我们决定研究血清中的人生长激素(STH)。在70例银屑病患者中,我们发现皮损范围与STH水平相关,STH水平是通过全天每2小时测定一次得出的。银屑病患者的平均STH水平是40例对照组平均水平的三倍。因此,可以得出结论,银屑病是由具有个体外显率的STH持续存在所引起的。

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