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对抵达东京机场时已死亡鸟类身上的甲型流感病毒进行分离和血清学特征分析。

Isolation and serological characterization of influenza A viruses from birds that were dead on arrival at Tokyo airport.

作者信息

Nerome K, Nakayama M, Ishida M, Fukumi H, Butterfield W K, Webster R G, Campbell C H

出版信息

Arch Virol. 1978;57(3):261-70. doi: 10.1007/BF01315090.

Abstract

Twenty-two strains of influenza A virus isolated from caged birds which had been imported into Japan from India and Thailand and had died druing transportation to Tokyo. Serological tests divided these strains into two groups. Viruses in the first group contained Hav7 hemagglutinin and were related antigenically to A/duck/Ukraine/1/63 [Hav7 Neq2]; viruses in the second group contained Hav4 hemagglutining and were related to A/duck/Czech/56 [Hav 4 Nav 1]. All strains contained Neq2 neuraminidase that was closely related to that fo A/equine/Miami/1/63[Heq2 Neq2] and A/duck/Ukraine/1/63[Hav7 Neq2]. It was concluded that the strains in the first group were Hav7 Naq2 and those in the second group were Hav4 Neq2; both group of viruses showed antigenic drift from the prototype strains.

摘要

从印度和泰国进口到日本并在运往东京途中死亡的笼养鸟类中分离出22株甲型流感病毒。血清学检测将这些毒株分为两组。第一组病毒含有Hav7血凝素,在抗原性上与A/鸭/乌克兰/1/63[Hav7 Neq2]相关;第二组病毒含有Hav4血凝素,与A/鸭/捷克/56[Hav 4 Nav 1]相关。所有毒株都含有与A/马/迈阿密/1/63[Heq2 Neq2]和A/鸭/乌克兰/1/63[Hav7 Neq2]密切相关的Neq2神经氨酸酶。得出的结论是,第一组毒株为Hav7 Naq2,第二组毒株为Hav4 Neq2;两组病毒均显示出与原型毒株的抗原漂移。

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