Yagi Y, Clewell D B
J Bacteriol. 1980 Aug;143(2):1070-2. doi: 10.1128/jb.143.2.1070-1072.1980.
The plasmid pAM alpha 1 in Streptococcus faecalis was found to be severely impaired in its ability to exhibit amplification (generation of tandem repeats of the tetracycline resistance determinant during extended growth in the presence of tetracycline) when harbored by the recombination-deficient host cell UV202.
当重组缺陷宿主细胞UV202携带粪肠球菌中的质粒pAMα1时,发现其在四环素存在下进行延长生长期间展现出扩增(四环素抗性决定簇的串联重复序列的产生)的能力严重受损。