移动分散遗传元件及其与致癌作用的可能关系。
Mobile dispersed genetic elements and their possible relation to carcinogenesis.
作者信息
Georgiev G P, Ilyin Y V, Ryskov A P, Kramerov D A
出版信息
Mol Biol Rep. 1980 Dec 31;6(4):249-54. doi: 10.1007/BF00777533.
PMID:6782446
Abstract
In this paper, a hypothesis is described according to which mobile dispersed genetic elements are related to endogenous viral genomes and may be involved in oncogenic transformation by uptaking cellular genes important for cellular growth. It is also possible that, in certain cases, they can switch off the genes involved in the control of differentiation.
摘要
本文描述了一种假说，根据该假说，移动分散遗传元件与内源性病毒基因组相关，并且可能通过摄取对细胞生长重要的细胞基因而参与致癌转化。在某些情况下，它们也有可能关闭参与分化控制的基因。
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