Tchurikov N A, Zelentsova E S, Georgiev G P
Nucleic Acids Res. 1980 Mar 25;8(6):1243-58. doi: 10.1093/nar/8.6.1243.
Ten clones containing the actively transcribed mobile dispersed gene Dm255 and its flanking sequences were selected from the HindIII bank of the Drosophila melanogaster genome. The Dm225 sequences present in these clones were identical while the flanking sequences were different in all of the clones analysed. Four of them contained, in addition to Dm225, other DNA sequences binding high amounts of cytoplasmic poly(A) + RNA. The properties of these new genes are similar to those of Dm255: they are also actively transcribed, multiple in copies, scattered throughout the genome, and located at varying genome sites which also were scattered throughout the whole genome of D. melanogaster. Thus, different mobile dispersed genes often appear as closely apposing units forming gene clusters in the genome.
从黑腹果蝇基因组的HindIII文库中挑选出10个含有活跃转录的移动分散基因Dm255及其侧翼序列的克隆。这些克隆中存在的Dm225序列是相同的，而在所有分析的克隆中侧翼序列是不同的。其中四个克隆除了含有Dm225外，还含有其他能结合大量细胞质多聚腺苷酸（poly(A)+）RNA的DNA序列。这些新基因的特性与Dm255相似：它们也被活跃转录，多拷贝存在，散布于整个基因组，并且位于不同的基因组位点，这些位点同样散布于黑腹果蝇的整个基因组中。因此，不同的移动分散基因常常以紧密相邻的单元形式出现在基因组中形成基因簇。
