Montplaisir J, Saint-Hilaire J M, Walsh J T, Laverdière M, Bouvier G
Neurology. 1981 Mar;31(3):350-2. doi: 10.1212/wnl.31.3.350.
Intravenous injections of naloxone (0.8 to 2.4 mg) were given to patients with focal epilepsy who had had electrodes implanted in cortical and subcortical structures. There were no changes in interictal spike activity, responses to electrical stimulation, of frequency of spontaneous seizures. These data do not support the hypothesis that opiate peptides are involved in human focal epilepsy.
对已在皮质和皮质下结构植入电极的局灶性癫痫患者静脉注射纳洛酮（0.8至2.4毫克）。发作间期棘波活动、对电刺激的反应以及自发性癫痫发作频率均未发生变化。这些数据不支持阿片肽参与人类局灶性癫痫的假说。
