Damian E, Ianăş O, Bădescu I
Endocrinologie. 1980 Oct-Dec;18(4):243-6.
Using the mouse uterus weight test and the rat ventral prostate weight test in basal conditions and under exogenous stimulation, the activity of 2 fractions of molecular weight above and under 10,000 daltons obtained by ultrafiltration of a melatonin-free pineal extract was tested against a total pineal extract and the same extract subjected to dialysis. The results showed that the larger fraction is predominantly anti-LH whereas the smaller fraction is anti-FSH. The antigonadotropic activity of the total and partially purified pineal extract against the effects of pineal melatonin and arginine-vasotocin is discussed.
在基础条件下以及外源刺激下，利用小鼠子宫重量试验和大鼠腹侧前列腺重量试验，对通过超滤褪黑素-free松果体提取物获得的分子量高于和低于10,000道尔顿的两个组分的活性进行了测试，将其与总松果体提取物以及经过透析的相同提取物进行对比。结果表明，较大的组分主要具有抗促黄体生成素（LH）作用，而较小的组分具有抗促卵泡生成素（FSH）作用。文中讨论了总松果体提取物和部分纯化的松果体提取物对松果体褪黑素和精氨酸血管催产素作用的抗促性腺活性。
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