Ma K, Sourkes T L
Agents Actions. 1980 Nov;10(5):395-8. doi: 10.1007/BF01968035.
The antimalarial drugs amodiaquine, quinacrine and chloroquine inhibit the catabolism of putrescine by the rat. Amodiaquine, the most potent of the three, does so in a dose-dependent fashion. This is attributed to the action in vivo of the drugs on diamine oxidase, an enzyme that is inhibited by them in vitro.
抗疟药物阿莫地喹、喹吖因和氯喹可抑制大鼠体内腐胺的分解代谢。三者中效力最强的阿莫地喹呈剂量依赖性地发挥此作用。这归因于这些药物在体内对二胺氧化酶的作用，该酶在体外会被它们抑制。
