Leach E D
Infect Control. 1981 Jan-Feb;2(1):26-30. doi: 10.1017/s0195941700053704.
Research leading to the development of Sporicidin, a new (synergized glutaraldehyde-phenate) sterilant and concentrated disinfectant, is reported. Microbial evaluation and shelf life testing of the new formulation was done using AOAC tests--Use-Dilution, Sporicidal, Tuberculocidal--and the E.P.A. Virucidal Test. Full-strength Sporicidin sterilizes (is sporicidal) in 6 3/4 hours at both 20C and 25C, and disinfects in 1-2 minutes. When diluted with 15 parts of tap water, Sporicidin is tuberculocidal, virucidal, and germicidal in 10 minutes, qualifying as a hospital disinfectant that will not "yellow" the hands or skin. The shelf life of activated Sporidicin, full strength or diluted 1 in 16, is 30 days. According to the data presented, which were the basis of E.P.A. registrations, Sporicidin is: (a) the fastest glutaraldehyde sterilant at room temperature, and (b) the only glutaraldehyde product that can be diluted below 2% and still qualify as a hospital disinfectant.
本文报道了新型（协同戊二醛 - 酚盐）消毒剂和浓缩消毒剂Sporicidin的研发相关研究。新配方的微生物评估和保质期测试采用了美国分析化学家协会（AOAC）的测试方法——使用稀释法、杀孢子法、杀结核菌法——以及美国环境保护局（EPA）的杀病毒测试。原液Sporicidin在20摄氏度和25摄氏度下6又3/4小时即可达到杀菌（杀孢子）效果，1 - 2分钟即可达到消毒效果。用15份自来水稀释后，Sporicidin在10分钟内可杀灭结核杆菌、病毒和细菌，符合不会使手部或皮肤“变黄”的医院消毒剂标准。活化后的Sporicidin，无论是原液还是1:16稀释液，保质期均为30天。根据作为EPA注册依据的数据，Sporicidin具有以下特点：（a）室温下最快的戊二醛消毒剂；（b）唯一一种可稀释至2%以下且仍符合医院消毒剂标准的戊二醛产品。
