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麻醉中的质谱分析。使用质谱仪监测麻醉气体和蒸汽时的问题。

Mass spectrometry in anesthesia. Problems in using mass spectrometer for monitoring anesthetic gases and vapours.

作者信息

Graham J M, Salamonsen R F, Kay B, Greer W, Parkhouse J, Stephenson D K, Beatty P

出版信息

Acta Anaesthesiol Belg. 1980;31(4):265-78.

PMID:6784436
Abstract

The use of mass spectrometers for total gas monitoring during anesthesia presents a number of problems which stem from the Cracking Pattern of the gases present, inlet design, viscosity variations, water vapour and machine deterioration. Some of these have been adequately solved, by making mechanical modifications to the inlet system, and by using more complex electronic circuitry to process the signals obtained. Remaining problems, however, still limit accuracy and ease of operation. CO2 measurements are particularly prone to error, especially when sampling halothane-containing gas which leads to significant internal production CO2. A study of the principal sources of error remaining in the machine suggests that the only definitive solution is to develop a microprocessor system which could cope with complex Cracking Patterns and non-linearities, and which would allow complete automation of the calibration procedure.

摘要

在麻醉过程中使用质谱仪进行全气体监测存在许多问题,这些问题源于所存在气体的裂解模式、进样口设计、粘度变化、水蒸气以及仪器老化。通过对进样系统进行机械改造,以及使用更复杂的电子电路来处理所获得的信号,其中一些问题已得到充分解决。然而,仍然存在的问题仍然限制了准确性和操作的简便性。二氧化碳测量特别容易出错,尤其是在对含氟烷的气体进行采样时,这会导致大量内部产生二氧化碳。对仪器中仍然存在的主要误差来源的一项研究表明,唯一确定的解决方案是开发一种微处理器系统,该系统能够应对复杂的裂解模式和非线性问题,并能使校准程序完全自动化。

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