Stokholm K H
Int J Obes. 1981;5(2):171-6.
Seventeen patients with stable body-weights who had undergone a jejuno-ileal bypass for obesity, and 25 obese patients matching in sex, age and height were studied. Median serum concentration of free triiodothyronine (3.7 pmol/l) in the jejuno-ileal bypass patients was significantly (P less than 0.001) decreased by 18 per cent (95 per cent confidence limits: 11-27 per cent). Correspondingly median serum concentration of total triiodothyronine (1.47 nmol/l) was significantly (P less than 0.0001) decreased by 18 per cent (95 per cent confidence limits:11-27 per cent). The medium serum concentrations of free thyroxine (27.5 pmol/l) and total thyroxine 94 nmol/l) were of equal size in jejuno-ileal bypass patients and obese patients. In the bypass patients the median serum concentration of thyroxine-binding prealbumin (3.9 micromol/l) ws significantly (P less than 0.05) decreased by 13 per cent (95 per cent confidence limits: 7-27 per cent), whereas no significant changes could be demonstrated in thyroxine-binding globulin.
对17名体重稳定且因肥胖接受空肠回肠分流术的患者，以及25名在性别、年龄和身高上匹配的肥胖患者进行了研究。空肠回肠分流术患者的游离三碘甲状腺原氨酸血清中位数浓度（3.7 pmol/l）显著降低（P<0.001），降幅为18%（95%置信区间：11%-27%）。相应地，总三碘甲状腺原氨酸血清中位数浓度（1.47 nmol/l）显著降低（P<0.0001），降幅为18%（95%置信区间：11%-27%）。空肠回肠分流术患者和肥胖患者的游离甲状腺素血清中位数浓度（27. pmol/l）和总甲状腺素血清中位数浓度（94 nmol/l）相当。在分流术患者中，甲状腺素结合前白蛋白血清中位数浓度（3.9 μmol/l）显著降低（P<0.05），降幅为13%（95%置信区间：7%-27%），而甲状腺素结合球蛋白未显示出显著变化。
