Domenech C E, Garrido M N, Machado de Domenech E E, Lisa T A
Mol Cell Biochem. 1981 Jan 28;34(2):95-9. doi: 10.1007/BF02354863.
The inhibition by atropine of cholinesterase from Pseudomonas aeruginosa has been studied in parallel with the membrane bound acetylcholinesterase from rat red cells. Acetylcholinesterase of rat red cells, like other animal cholinesterases, was competitively inhibited while the cholinesterase from Pseudomonas aeruginosa was partially non competitively inhibited by atropine. These results clearly indicated a different behavior of cholinesterase from Pseudomonas aeruginosa in comparison with the enzyme of Pseudomonas fluorescens and other animal cholinesterases.
已将铜绿假单胞菌胆碱酯酶受阿托品的抑制作用与大鼠红细胞膜结合乙酰胆碱酯酶进行了平行研究。大鼠红细胞的乙酰胆碱酯酶与其他动物胆碱酯酶一样，受到竞争性抑制，而铜绿假单胞菌的胆碱酯酶则受到阿托品的部分非竞争性抑制。这些结果清楚地表明，铜绿假单胞菌的胆碱酯酶与荧光假单胞菌的酶及其他动物胆碱酯酶相比，具有不同的行为。
