Kelly J J, Sharbrough F W, Daube J R
Neurology. 1981 May;31(5):581-9. doi: 10.1212/wnl.31.5.581.
The records of 23 consecutive patients with myoclonus who were seen during a 16-month period were analyzed prospectively. The patients were divided into two groups: epileptic and nonepileptic. The epileptic patients had focal and stimulus-elicitable myoclonus with enlarged somatosensory evoked potentials and enhanced long-loop reflexes, and they responded well to anticonvulsants, especially clonazepam and valproic acid. The nonepileptic group had massive and spontaneous jerks with normal-sized somatosensory evoked potentials and long-loop reflexes, and they responded poorly to anticonvulsants. Evaluation of these clinical and electrophysiologic characteristics can help in the classification of obscure movement disorders and in predicting responses to therapy.
对连续23例在16个月期间就诊的肌阵挛患者的记录进行了前瞻性分析。患者被分为两组：癫痫性和非癫痫性。癫痫性患者有局灶性且可由刺激诱发的肌阵挛，体感诱发电位增大，长环反射增强，且对抗惊厥药，尤其是氯硝西泮和丙戊酸反应良好。非癫痫性组有大量自发性抽搐，体感诱发电位和长环反射大小正常，且对抗惊厥药反应不佳。对这些临床和电生理特征的评估有助于对不明原因的运动障碍进行分类，并预测对治疗的反应。
